hrp0089p3-p017 | Adrenals and HPA Axis P3 | ESPE2018

Non-classic Congenital Adrenal Hyperplasia Causing Alleles among Adolescent Girls with PCOS – Genetical Study

Lidaka Lasma , Lazdāne Gunta , Gailīte Linda , Dzivite-Krisane Iveta

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in adult women. Syndrome is characterised by hiperandrogenism, oligo/amenorrhoea and polycystic ovary morphology in ultrasound. Clinical signs of the syndrome usually start already during adolescent years. Non-classic congenital adrenal hyperplasia (NCAH), caused by several mutations in CYP21A2 (6p21.3) gene, is the most common differential diagnosis for girls presented with symptoms of P...